The MRAP Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to MRAP. This antibody recognizes Human, and Mouse antigen. The MRAP Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Function: Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.
Subunit Structure: Homodimer and heterodimer. Forms antiparallel homodimers and heterodimers with MRAP2. Interacts with MC1R, MC2R, MC3R, MC4R and MC5R.
Similarity: Belongs to the MRAP family